Prime (USP Labs)

User rating
3.8
out of 5
149 user reviews

4 forum posts

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Prime (USP Labs)

Obviously, everyone loves the effects of androgenic-anabolic substances such as pro-hormones, pro-steroids (the select few that work). They allow you to gain muscle and strength, while losing fat. Unfortunately, they also come with a set of drawbacks, including prostate issues, gynecomastia, cardiovascular problems and one that many are likely very familiar with – Testosterone suppression & post cycle therapy (PCT). Every time you stop using such androgenic-anabolic substances, you are invariably required to take a number of other products designed to help your body recover endogenous testosterone production. If you don't, you'll lose the muscle and strength you've gained and gain back the fat. In fact, you'll end up right back where you started or worse.

IS THERE A BETTER WAY?
What you need is something that is highly anabolic, yet doesn't suppress testosterone production. Sounds easy; yet such compounds are rarer than a 1903 T3 Honus Wagner (for all you baseball card collectors out there). By now, you expect USPlabs to deliver unique products and formulations others simply cannot.

We have, in fact, found a formula which produces significant anabolic activity in humans without hormonal suppression!

In our own pilot study, a group of 12 exercising men were found to experience the following, on average, over a 30-day period while using USPLabs Prime:

  • 4.29 lbs increase in body weight
  • 6.37 lbs increase in lean body mass
  • 2.08 lbs decrease in fat mass
  • 40.83 lbs increase in bench press strength (3 RM)
  • 54.58 lbs increase in squat strength (3 RM)

Furthermore, just to make certain the product isn't simply acting as an androgen and exerting these effects, we had Luteinizing Hormone (LH) and total and free testosterone levels measured. Luteinizing Hormone is the hormone responsible for allowing the testicles to produce testosterone and is often decreased when a substance is acting as an androgen, though there are some exceptions. What we found was that there was no statistically significant decrease in LH or testosterone in the subjects taking USPLabs Prime .

How does USPLabs Prime work?
This is an interesting question. Because we found no evidence for androgenic activity, we believe it to have anti-glucocorticoid effects, providing a possible mechanism for the increase muscle mass seen with USPLabs Prime. It may also be something related to improved nutrient absorption or utilization. In fact, the recomposition effects - even on subjects who were making poor food choices and consuming 750-1000kc/cal surplus per day – are downright amazing. It's not something recommended, but when testers are pounding buffalo wings and pizza while putting on massive size and strength – AND getting leaner – you can't help but take notice.

What can I expect to experience when taking USPLabs Prime?

  • Permanent Muscle Gains – Hormonal levels are not affected, therefore there' s no drop-off – What you gain is yours to keep!
  • Does not cause shut-down or suppression!
  • Promotes Muscle Gain of Thick, Dense Variety!
  • Extremely Potent Re-composition Effects – Even test subjects consuming 750-1000 calories a day ABOVE baseline lost bodyfat while gaining mass & strength!
  • Enormous Strength Gains – Own The Weight Room!
  • Incredible Recovery Speed – Feel like you've had a two-week layoff – even the day after the most intense workout of your life!
  • All-Day Muscle Fullness/Hardness – Your Muscles Will Feel Like Granite!
  • Balls-To-The Wall Training – Train harder and longer than you ever have – and like it!
  • Incredible Euphoria – Feel Like Superman!
  • Safe to use in competition – all-natural ingredients - WILL NOT cause positive drug test!

That's an AVERAGE of 40.83 pounds on the bench press for a 3 rep max in just 30 days! The subject that made the greatest improvement gained 62 pounds on his 3RM again, in just 30 days. (complete study recap is a little further down in this letter). Squat numbers went up big time as well with a 54.58 pound average increase in 30 days with the top subject gaining 81 pounds on his 3RM squat.

Sure, we chose very dedicated subjects who we knew would really put USPlabs Prime to the test, but that's the beauty. These guys have been lifting for so long it's very difficult for them to put on significant size or strength over the course of a year, let alone 30 days! This proves just how strong this stuff actually is! And, let's be honest, even if you gain half of what these guys did, you'll be happier than a fat kid at a pizza buffet.

Because the increase in lean body mass cannot account for it completely, it is believed that a neuromuscular effect is involved. Evidence suggests that an increase in acetylcholine (a neurotransmitter) levels, which may increase muscle fiber recruitment and/or the resistance to fatigue of fast twitch skeletal muscle is responsible for the large increase in muscular strength seen in those using USPLabs Prime.

How long until USPLabs Prime starts to work?
Most have noticed increased workout production and overall body hardening within a few days. However, everyone agrees by the end of week 3 USPLabs Prime is in full force – running through your veins and demonstrating the unique anabolic effects only it can!
Here's a timeline based upon user feedback:

Week 1
You will begin to experience the power of USPLabs Prime during your workouts. Weight will begin to feel lighter than normal and you'll begin to have great workout after great workout - even on days you don't necessarily enter the gym with the highest amount of intensity or energy. You will find the ability to summons strength almost at will. You also may begin to notice the anabolic effects kicking in where you're whole body will begin to harden.

Week 2
You'll continue to have awesome workouts. During these workouts you'll begin to feel an intense full-body muscle fullness and hardness. While it's a pump per say, it's very unique and unlike that from creatine, NO or other products. In addition, the super-human recovery abilities will begin to kick in. Remember, some pro athletes use Pharmaceuticals to significantly increase recovery so they can train harder, longer & more frequently. USPLabs Prime significantly speeds the muscle repair process, leading increase training intensity, volume & frequency.

Week 3
This is the magical week our subjects cannot stop talking about. For most, by the end of Week 3 is when USPLabs Prime REALLY begins to impart its force upon your body. You'll fly through your workouts, your body will be hard as a freakin rock – all day long.

Week 4
The great thing about USPLabs Prime is it just continues to get better and better the longer you use it. During week 4 is where you'll begin to set personal records frequently. Weights that were heavy in the past are going up like butter – and you feel like THE MAN. By this point you should be getting plenty of compliments from those around you noticing you're -bigger- and -stronger-. And don't be surprised that your body is in such an anabolic state that you get a chest pump when you're squatting!

Week 6 and Beyond
At this point you should have put on some serious, REAL muscle mass. It will be thick and dense, not simply water weight. Some subjects have even noted their asthetics have changed and they now have a V-taper that they've never had before. And, this may be very hard to believe – but many users have reported that after taking USPLabs Prime, their bodies have permanently changed. They have more muscle (thick and dense) with a more athletic build. Now, we're not saying that is going to happen to you, but many of our tests subjects are reporting this.

Have any studies been done on USPLabs Prime?
Yes. And, by the looks of it USPLabs Prime is, without a shadow of a doubt, to be the biggest breakthrough in supplementation in a long, long time. Maybe EVER.

12 SUBJECT 30-DAY PILOT STUDY

We commissioned a pilot study using 12 experienced weight lifters. We were VERY selective in our subjects. We wanted the best of the best. Sure, it was a pain in the ass to compile such a group – but it was well worth it! These were guys who had at least 10 years of lifting experience and weighted at least 190 pounds. We required they averaged a minimum of 3 workouts per week for the last 3 years to ensure any of the results would not be skewed. In other words, if these guys can grow and get stronger on USPLabs Prime, than ANYONE can - as the longer you lift, the more difficult it becomes to make any gains in muscle and strength – let alone significant progress.

An Evaluation for Efficacy of a Dietary Supplement Designed to Augment Lean Body Mass, Improve Strength, Decrease Fat Mass & Alter Hormone Levels Background:

USPLabs Prime  is a dietary supplement marketed for its purported ability to increase lean body mass, decrease body fat, and improve strength output via an anabolic effect in exercising adults.

Objective: The purpose of this open-label, single-arm, non-randomized pilot study was to determine what effect USPLabs Prime  had upon body composition (i.e. lean body mass and fat mass), strength and hormones in normal, exercising adults.

Methods: After volunteering for study, 12 male subjects were assessed for body composition prior to supplementation and once more after 30 days. In addition, blood was drawn once pre and post supplementation and evaluated for vitals, Total Testosterone, Free Testosterone and Luteinizing Hormone (via LabCorp). The dosage of USPLabs Prime  was six capsules in three evenly divided doses per day with meals. Changes in body composition were assessed via 7 site skin fold testing.

Results: Upon comparison to the baseline, the mean increase in body weight was 4.29 lbs. Further calculations revealed decreased fat mass of approximately 2.08 lbs with an increase in lean body mass of 6.37 lbs. In addition, mean testosterone levels (Free and Total) and Luteinizing Hormone levels were not significantly affected.

Conclusions: The preliminary data gathered suggest the ingredients in USPlabs Prime  can increase body weight and lean body mass, while decreasing fat mass in exercising adult males. In addition, bench press and deadlift strength improvements were significant.

Do I need to Cycle USPLabs Prime?
Well, you won't want to come off! And since it does not statistically affect hormonal levels one way or another, you can stay on for long periods. But, just to be safe, we suggest 12 weeks on, 4 weeks off. Or at least two, 3 week breaks per year.

Does it have any side effects?
People are training so intense and heavy and gaining muscle & strength at such a rapid pace, that the Central Nervous system cannot keep up. So that is why we recommend using USPLabs Prime on a 5 days on, 2 days off schedule. Certainly, it can be used every day, just take this as fair warning if you end up crushing your CNS because you're training balls-to-the-wall everyday! You will be training as such a heightening level, both mentally and physically, you just have to monitor yourself.

Can I stack USPLabs Prime with any other supplements?
The ultimate stack is ALWAYS going to include Anabolic-Pump due to it's ability to increase the effectiveness of every supplement you take & properly utilize your food intake – which is critical to any plan – even steroids. In addition, adding PowerFULL to the mix forms what we believe to be the greatest stack ever assembled.

Should I use it on a bulk or cut?
You really can use on either. In fact in our 12 subject pilot study demonstrated the following. And that was just USPLabs Prime alone. Stacked with Anabolic-Pump & PowerFULL, you're talking serious, physique-altering results.

Test subjects have noted an increase in hunger. This is a sure sign your body is in an anabolic state. The good news is, USPLabs Prime has demonstrated a very potent nutrient portioning effect so these extra calories are put to good use.

What else can I stack USPLabs Prime with?
Pretty much anything. It will dramatically enhance the results of every stack you are on. Whether you are bulking, cutting, or re-comping, USPLabs Prime absolutely needs to be a part of your stack.

USPLabs Prime contains two extremely potent, novel ingredients.

SuperAnabolic
SuperAnabolic is a rare species of herb in the same family as Tribulus Terrestris. However, once you try USPLabs Prime you'll soon realize the comparisons stop there. The steroidal glycosides contained in USPLabs Prime make the saponins of tribulous terrestris look like the placebo!

Steroidal Gylcosides
Tribulus Aquaticus contains active steroidal components called steroidal glycosides. However, the components in USPLabs Prime are unique to our specific extract of Tribulus Aquaticus and have not been found in any other compound in the world. These steroidal glycosides are believed to exert their anabolic effects through non androgen receptor-mediated mechanisms, perhaps by possessing anti-glucocorticoid activity similar to pharmaceutical compounds such as methandrostenolone (D-bol). In any case, it's obvious that these steroidal glycosides allow for a retention of nitrogen and either a decline in the catabolic processes related to skeletal muscle or an improvement in protein synthesis; the end result of which is increased muscle mass.

CellMend – King Of Medicines
The Ayurvedic medicinal system points to a wonder-fruit called terminalia chebula. Its viewed as one of the most potent CNS and body adaptagenic compounds the world has ever seen. It's proposed that terminalla chebula balances the entire body mentally and physically - placing your body in a perfect state of balance during times of intense stress. Terminalia Chebula is called the -King of Medicines-. It's always listed first in the Ayurvedic meteria medica because of its extraordinary powers of healing. According to Charak, the most eminent Ayurvedic physician, Terminalia Chebula is the best fruit for rejuvenation and disease cure.

Additional Terminalia Chebula benefits:

  • Also contains antioxidant components, which indicates it may increase the life of tissues.
  • In Ayurveda, Terminalia Chebula is used for 'Srotoshodhana' or purifying the channels of body
  • It's thought to stimulate & protect the liver.
  • When taken with meals, it's believed to sharpen the intellect, increases strength, stimulates the senses, expel urine, stool and other waste materials from the body.
  • It's used in nervous weakness & irritability. It promotes the receiving power of the five senses.
  • Based on its comprehensive properties, it promotes appetite and helps indigestion.

Cellmend Research
Oxidative Stress and Lipid Peroxidation are recently being implicated in a wide-range of physiological disorders, due to their damaging effects on cell transcription and homeostasis. Oxidative Stress is the production of Reactive Oxygen Species (ROS) such as peroxides and free radicals, as a result of an imbalance in cellular reduction – that is, as the mitochondria metabolize energy, they undergo cellular respiration; this process produces ‘reactive oxygen', and damaging reactive oxygen species arise when the body cannot readily detoxify the intermediates in this process. Oxidative Stress then ensues when the body cannot repair the stress from the initial reaction, or as mentioned, readily redox the productive aspect of cellular respiration. The tangible effects of OS are inhibited DNA and protein transcription, membrane instability, aptosis, or ultimately, necrosis. Such conditions play a prominent role in degradative neural diseases such as Parkinson's and Alzheimer's.

Lipid Peroxidation (LP) is a highly similar process, and involves the degradative oxidation of cell plasma membranes (as cell membranes are comprised almost entirely of lipid strains).

Ultimately, LP results in cell membrane instability, and acute cellular damage. It is also implicated in a wide-range of physiological disorders. As a result of these damaging processes, much research is being conducted in the field of anti-oxidants – or, compounds which combat the oxidative stresses of cellular respiration and free radical production. Recent research has revealed Terminalia Chebula (TC) has both potent secondary and direct effects on oxidative stress. TC has also been shown to mitigate hepatic oxidative stress, via its aforementioned anti-oxidative and membrane stabilizing capacities.

Average user rating from: 149 users

Overall rating
3.8
Euphoria (5 ratings)
4.1
Anxiety reduction (1 rating)
0.5
Focus (4 ratings)
5.0
Motivation (2 ratings)
5.0
Fat loss (9 ratings)
3.5
Vascularity (5 ratings)
4.1
Anti-catabolic (1 rating)
5.0
Endurance (8 ratings)
4.4
Suppressed appetite (3 ratings)
3.5
Texture (4 ratings)
5.0
Muscle gain (50 ratings)
4.7
Strength (85 ratings)
4.3
Physical energy (16 ratings)
4.6
Low side effects (3 ratings)
3.5
Recovery ability (16 ratings)
4.4
Pump (21 ratings)
4.5
Aggression (4 ratings)
2.5
Increased appetite (3 ratings)
3.0
Taste (5 ratings)
0.5
Safety (3 ratings)
5.0
Value for money (49 ratings)
2.4
Libido (6 ratings)
3.8
Ingredient profile (5 ratings)
3.2
Reported side effects (adverse events)

Acne/oily skin 1 user (1%)
Testicular atrophy 1 user (1%)
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Muscle gain
Libido
Fat loss
Euphoria
Taste
 


1 of 2 people found the following review helpful

Written by

Overall rating
2.9
Muscle gain
3.5
Strength
3.0
Physical energy
0.5
Low side effects
0.5
Recovery ability
4.0
Pump
4.0
Aggression
0.5
Increased appetite
4.5
Taste
0.5
Safety
5.0
Value for money
3.0
Libido
3.5
Testicular atrophy
Acne/oily skin
The pill works. Plain and simple read any other good review and thats what it did for me.

However, it tastes like coffee, meat tenderizer, butthole, and chocolate when you put the pills in your mouth, making it almost impossible to stomach or swallow.

It also has made me want to eat like a horse and made my face breakout like a pubescent kid....

Im gonna stop taking it and just find something else cuz i cant handle it. If you can handle putting poop flavored pills in your mouth, and having acne then this is the pill for you.
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3 of 4 people found the following review helpful

Written by

Overall rating
4.4
Muscle gain
5.0
Strength
5.0
Physical energy
3.5
Low side effects
5.0
Recovery ability
5.0
Pump
4.0
Aggression
4.0
Increased appetite
4.0
Safety
5.0
Value for money
4.5
Libido
3.5
I am loving this stuff. I ran Prime for 6 weeks (9 caps for first ten days, then 6 caps a day) and gained 11 pounds and actually dropped a quite a bit of bodyfat. So lean mass gain was 12-13 pounds. Pretty impressive, especially since I didn't have any side effects. Strength gains were stupid...went from 285 for 6 on the squat to 325 for 8! Bench went from 255 for 5 to 315 for 6! Pull-ups went from 30 pound for 6 to 65 pounds for 5. I didn't really believe the permanent gains were true because I've done pro-hormones & designers before and always lost most of my gains even when I did proper PCT, but its true. here I am 4 weeks after stopping Prime and I have actually gained 2 more pounds (bodyfat the same) and my strength is still going up. Seems to have some residual effect. Needless to say these results are WAY more than i expected so of course I'm thrilled. Good stuff! Will buy again!
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20 of 25 people found the following review helpful
admin

Written by - Top 50 reviewer - View all my reviews

Overall rating
1.1
Fat loss
0.5
Euphoria
0.5
Muscle gain
0.5
Strength
0.5
Low side effects
5.0
Recovery ability
0.5
Increased appetite
0.5
Safety
5.0
I haven't reviewed anything in a while, and that's because I usually just stick to my most basic supplements. But once in a while, I like to try something new, especially if there's a lot of hype around it.

The hot thing on the market these days seems to be USPlabs Prime. Since my life (including diet and exercise) is very structured and consistent, I thought I could provide some honest feedback. First, a couple of things about me: I have 20 years of lifting experience, and never really had an extended layoff. I'm fairly ectomorphic, with a small degree of mesomorphy. I can gain muscle (along with some fat) quite easily though; it's simply a matter of eating more quality food. The muscle and strength just increase without any extra effort on my part.

In their pamphlet that comes with the bottle, USPlabs states, "We could have easily selected subjects who hadn't worked out in a while - so the results showed a ridiculous amount of muscle gain that steroids won't even provide. Certainly other companies are doing just that... That's why we picked testers who would almost ensure USPlabs Prime DIDN'T work. Because we knew if it worked on these guys, it could work on anyone. And in the end - they still made significant progress despite our efforts to the contrary!" (Maybe next time, USPlabs can pick *me* as one of their test subjects!)

Anyway, I did *not* increase my food consumption whilst taking the supplement, which I did on the suggested 5 on, 2 off schedule. That's because it clearly states in the pamphlet, "Should I use it on a bulk or cut? You really can use [it] on either." Mine was neither, so according to them, I should have gained lean body mass, and lost at least a small amount of fat mass.

The results were extremely disappointing. I started the cycle with an open mind, expecting nothing, but not purposely doing anything to skew the results negatively. I felt none of the "incredible euphoria" ("Feel Like Superman!") that they claim is real-world feedback - indeed, I believe this could be a placebo effect. If you believe you're experiencing enormous strength gains, you will naturally be in a euphoric state.

Certain things in the pamplet strike me as rather suspicious, and nothing other than hype intended to get people to believe in their claims:
1) "The ingredients in USPlabs Prime are *extremely* rare... this stuff is *so rare and unique* that even the raw material suppliers were confused! ...because of the time scheduling of how these compounds are grown and harvested, if anyone even attempts to claim they have a similar product before the [sic] April 2010 you know they are full of shit!"
2) Their claims about how one of its two main ingredients is viewed as one of the most potent CNS compounds the world has ever seen, and how the "5 on/2 off scheduling delivers all of the positive benefits without the CNS breakdown." This ingredient is Terminalia Chebula. According to http://www.holistic-herbalist.com/terminalia-chebula.html, http://www.ayurveda-herbal-remedy.com/indian-herbs/terminalia-chebula.html and http://www.alternative-healthguide.com/ayurveda/terminalia_chebula.htm (all on page 1 of Google's search results for this ingredient), the main effects of this compound do not include CNS effects. Also, what exactly *is* "CNS breakdown?" According to what I could find, it is one of the physiological changes that accompany aging. Hardly something that accompanies excessive exercise nor administration of "CNS compounds." On the same topic, CNS compounds are generally neurological and psychiatric drugs, so it's hard to see how this fits in with anabolism or recovery.

I have read a lot about how many other users are getting the purported benefits from Prime, so I cannot say that your experiences with it will be similar to mine. But I do strongly suspect that there is group psychology at play here.
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