Support this site, buy Dren from affiliate retailers (see all Dren prices and serving sizes):
|Shipping: Flat rate - $5.95 within the US||$0.60||
Shipping: Flat rate - $4.95 within the US
5% off orders > $200
10% off orders > $1000
Free gift with orders > $75
I'll Pump You Up
|5% off any order: Code - SubstanceReviews||$0.70||
DREN (Drenbuterol) belongs to a powerful new class of compounds called mesolimbic beta agonists, which have extremely powerful fat burning and euphoric activities. Drenbuterol is a patent pending compound scientifically formulated to stimulate both metabolic and mesolimbic pathways for extreme thermogenic fat burning and neurotropic “feel good” sensory. Each DREN capsule provides the maximum 409mg dose of Drenbuterol and should only be administered once daily and not be used with other stimulants. When taken as directed, DREN will help stimulate the thermogenic fat burning process, increase energy levels, suppress appetite and illicit a state of heightened mental euphoria.
DREN stimulates lipolysis as well as psychoactive activity by using the newest, most powerful and exciting fat loss ingredient in existence called Beta-Methoxy PEA (exclusive to DREN). Please pay special attention to the word Methoxy and do not overlook it, as it makes all the difference in the world and is one reason why DREN's effectiveness is simply unmatched.
Beta-Methoxy PEA works in part by increasing noradrenaline (NA) release from sympathetic nerve terminals. This increase in noradrenaline activates adrenergic receptors, which increases cAMP levels in fat cells (increasing its breakdown) and muscle cells (increasing protein synthesis).
Unfortunately, in response to beta-adrenergic stimulation (just what happens when taking Ephedra), negative feedback mechanisms are activated as well. Stimulation of the Alpha 2 receptor as well as the production of phosphodiesterases and adenosine occurs. The alpha 2 receptor, phosphodiesterases and adenosine try to slow down or halt the fat burning process which is the reason why caffeine and aspirin were often added to Ephedra products. Caffeine and aspirin overcame much of the negative feedback mechanisms and made Ephedra even better. DREN is no exception because it works in many of the same exact ways that Ephedra does (but even better) so measures had to be taken to maximize its actions in the body and minimize these negative feedback mechanisms.
In addition to Beta-Methoxy PEA, Caffeine, Yohimbine HCL and 5-HTP have been added to the formula. Yohimbine HCL has been added to the formula as it increases the effectiveness of DREN by its actions on the Alpha 2 receptor while Caffeine has the ability to inhibit phosphodiesterase activity and interfere with the adenosine receptor. This combined with its ability to prevent some noradrenaline re-uptake increases the effectiveness of DREN in a synergistic fashion. 5-HTP has psychoactive actions in and of itself as well as synergisms to the overall fomula.