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3 years 5 months ago #4911

So I think this product is as stage II trials now, here is a video:

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3 years 5 months ago #4914

That guy talks so slowly, lol.

Do you have a link to the study?

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3 years 4 months ago #4922

Here are the links, thanks for sending them to me:

Brief report: intraarticular sprifermin not only increases cartilage thickness, but also reduces cartilage loss: location-independent post hoc analysis using magnetic resonance imaging

CONCLUSION:
Sprifermin not only increases cartilage thickness, but also reduces cartilage loss. Subject-specific, location-independent analysis of both cartilage thinning and thickening represents a sensitive and informative approach for studying the effects of disease-modifying OA drugs.

Intraarticular sprifermin (recombinant human fibroblast growth factor 18) in knee osteoarthritis: a randomized, double-blind, placebo-controlled trial
CONCLUSION:
No statistically significant relationship between treatment group and reduction in central medial femorotibial compartment cartilage thickness was observed; however, prespecified structural secondary end points showed statistically significant dose-dependent reductions after sprifermin treatment. Sprifermin was not associated with any local or systemic safety concerns.

Last Edit: 3 years 4 months ago by admin.

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